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Year : 2022  |  Volume : 1  |  Issue : 1  |  Page : 63-66

The diagnostic conundrum of lupus vulgaris versus cutaneous sarcoidosis

1 Department of Dermatology, AIIMS Raebareli, Raebareli, Uttar Pradesh, India
2 Department of Pharmacology, AIIMS Raebareli, Raebareli, Uttar Pradesh, India
3 Department of Pathology and Lab Medicine, AIIMS Raebareli, Raebareli, Uttar Pradesh, India

Correspondence Address:
K Geetha
Department of Dermatology, AIIMS Raebareli, Raebareli, Uttar Pradesh
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jpdtsm.jpdtsm_12_22

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Infection with Mycobacterium tuberculosis causes tuberculosis (TB). Lupus vulgaris is one of the most common forms of cutaneous TB, which affects 1%–2% of TB patients. Sarcoidosis is a multisystem granulomatous disease with an unknown origin, and skin involvement is the second most common symptom. Both TB and sarcoidosis are granulomatous diseases. Depending on investigations, it is often hard to distinguish sarcoidosis from TB, especially when serum angiotensin-converting enzyme levels are high in certain cases of TB with negative acid-fast staining in the biopsy specimen. This is a report of two patients where there was trouble distinguishing between sarcoidosis and TB based on laboratory reports but was eventually diagnosed with cutaneous TB based on the Mantoux, QuantiFERON-TB Gold test, and histopathological pattern. Anti-TB therapy was administered to those patients, and the skin lesions resolved completely.

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